Protein Details: Glutamate receptor 3.4
Protein ID
ICDB_Pro_1244
Protein Name
Glutamate receptor 3.4
Gene Name
GLR3.4; GLR4; GLUR3; At1g05200; YUP8H12.19
Organism
Arabidopsis thaliana (Mouse-ear cress)
Length
959 amino acids
AlphaFoldDB
AF-Q8GXJ4-F1-model_v4.pdb
Function
Glutamate-gated receptor that probably acts as a non-selective cation channel; at least in hypocotyls (Probable). Can be triggered by Asn; Ser; Gly and; to a lower extent; Ala; Cys and Glu. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells (Probable). Plays an important role in the calcium-based fast transmission of environmental stress. Acts as a negative regulator of lateral root initiation and development. May restrict primordia numbers and position along the root axis by a signaling process originating in the phloem. AtGLR3.4-mediated cytosolic calcium influx may be involved in the regulation of seed germination under salt stress by modulating sodium accumulation through the SOS pathway.
Sequence
Ligand Binding
Binding Site
Disease
Location
Highly expressed in roots and at lower levels in leaves and siliques (PubMed:12082126). Expressed in seedlings; cotyledons; roots (e.g.g.g. root hairs; epidermis and cortex cells); stems; leaves (e.g. vascular bundles and hydathodes); and siliques (PubMed:15864638). Expressed in root phloem (PubMed:23590882)...
DOI ID
10.1093/oxfordjournals.molbev.a004165; 10.1038/35048500; 10.1111/tpj.13415; 10.1126/science.1071006; 10.1007/s00425-005-1551-3; 10.1126/science.292.5521.1486b; 10.1104/pp.107.108134; 10.1016/j.bbabio.2010.11.008; 10.1104/pp.112.197509; 10.1105/tpc.113.110668; 10.1093/pcp/pcy034
RefSeq
NP_001030971.1 [Q8GXJ4-1]; NP_001320828.1 [Q8GXJ4-2]; NP_001320831.1 [Q8GXJ4-1]; NP_172012.2 [Q8GXJ4-1]